6 ECG Labs & Cardiac Monitoring Companies for Clinical Trials in 2026

Cardiac safety data is a required endpoint in most drug development programs, and the vendors supporting it range from centralized ECG core labs that read and adjudicate data on a sponsor's behalf to the device makers whose hardware captures that data in the first place. An ECG lab typically provides the technicians, cardiologist overreads, and QT/QTc analysis that regulators expect, while a growing set of portable and wearable ECG devices now make it possible to capture that same data outside a traditional clinic visit. For Sponsors and CROs evaluating an ECG lab for a clinical trial, the choice often comes down to whether a study needs full-service centralized reading or a validated device to pair with an existing core lab relationship.

The companies below, presented in no particular order, cover both sides of that equation: dedicated ECG core labs that read and adjudicate cardiac safety data, and the device and software providers whose hardware and platforms capture it, including options built for decentralized and home-based monitoring.

HeartcoR Solutions

HeartcoR Solutions operates as an ECG core lab providing cardiac event monitoring, Holter monitoring, and centralized ECG data analysis, including QT/QTc cardiac safety analysis, to pharmaceutical, medical device, and biotech sponsors. Headquartered in the Chicago area, the company states its systems support both site-based and decentralized clinical trials with 24/7 project management and data tracking. In 2025 HeartcoR partnered with Wellysis for exclusive rights to its S-Patch wearable ECG device, and in 2026 it partnered with Image Analysis Group to combine cardiac safety and imaging core lab services under a single workflow.

Biomedical Systems

Biomedical Systems provided centralized cardiac safety, medical imaging, and respiratory endpoint services for clinical trials, and the company states it worked with more than 11,000 investigative sites across 75 countries during its independent operation. Founded in 1975 in Missouri, the company introduced its TruVue wireless ambulatory ECG monitoring system in 2010 before being acquired by ERT (now Clario) in 2017, folding its cardiac safety, imaging, and respiratory services into that company's broader endpoint technology platform. Biomedical Systems' cardiac safety capabilities continue to operate today as part of Clario.

BioTelemetry (Philips)

BioTelemetry provides ambulatory cardiac diagnostics and monitoring services, including short- and long-term Holter monitoring, event recorder services, and Mobile Cardiac Outpatient Telemetry, alongside a separate clinical research testing business supporting clinical trials. Founded in 2004 as CardioNet and based in Malvern, Pennsylvania, the company monitored more than one million patients annually before Philips acquired it in 2021 for approximately $2.8 billion. BioTelemetry now operates as part of Philips' Connected Care business segment.

AliveCor

AliveCor develops FDA-cleared personal ECG devices, including the KardiaMobile and KardiaMobile 6L, which the company states are the most clinically validated personal ECG products available and are used to detect atrial fibrillation, bradycardia, tachycardia, and other rhythm abnormalities from a 30-second recording. Based in Mountain View, California, AliveCor's KardiaMobile 6L received FDA clearance for QTc interval measurement, extending its use into cardiac safety monitoring for decentralized and hybrid clinical trials. AliveCor's devices are used by biopharma companies, CROs, and health systems worldwide.

QT Medical

QT Medical develops the PCA 500, an FDA-cleared 12-lead resting ECG device the company states is compact and cloud-based enough to bring hospital-grade ECG testing into telemedicine, home care, and remote settings. Founded in 2013, the company partnered with HeartcoR Solutions to make its QHeart electrode-strip technology available within HeartcoR's clinical trial cardiac safety services, and it launched Xpress ECG, a mail-order home ECG testing service, in 2020. QT Medical's PCA 500 has been validated head-to-head against conventional hospital 12-lead ECG systems.

Global Instrumentation

Global Instrumentation provides customized cardiac diagnostic and monitoring solutions, including its M12A software platform, which the company states powers ambulatory ECG monitoring services with both real-time algorithms for applications like mobile cardiac telemetry and retrospective algorithms for continuous long-term recordings such as extended Holter monitoring. The company supplies its technology to clinical researchers, cardiac monitoring service providers, and medical technology developers building their own ECG data collection capabilities. Global Instrumentation positions its platform as infrastructure for other cardiac monitoring services rather than a direct-to-sponsor core lab.

Explore the full ECG landscape

The companies above represent a portion of a much larger field.

Diligent's platform includes over 70 ECG Vendors, many with Vendor qualification data available on demand. Book a demo to explore Diligent's full vendor discovery database.

This article is intended as an informational overview of vendors operating in this space. Inclusion on this list does not constitute an endorsement, recommendation, or qualification by Diligent.