12 eCOA/ePRO Companies for Clinical Trials in 2026

Electronic clinical outcome assessment has become the standard for capturing how a patient feels and functions during a trial, replacing paper diaries and questionnaires with platforms that patients, clinicians, and observers can complete on a phone, tablet, or web browser. An eCOA provider might offer a standalone patient-reported outcomes tool, a broader platform that bundles eCOA with EDC, RTSM, and eConsent, or a core lab model that pairs eCOA with cardiac safety and imaging services. For Sponsors and CROs evaluating an eCOA vendor, the fit often comes down to whether a study needs a dedicated best-of-breed eCOA specialist or a unified eClinical platform where eCOA is one module among several.

The companies below, presented in no particular order, span that range. Between them they cover dedicated eCOA specialists, unified eClinical platforms bundling EDC, IRT, and eConsent, and core labs that pair eCOA with cardiac safety or imaging services.

Kayentis

Kayentis provides electronic Clinical Outcome Assessment and decentralized clinical trial technology, and the company states its platform has supported digital data collection across more than 280 clinical trials in 85 countries, employing 120 languages. Active in clinical development since 2003 and headquartered in Grenoble, France, the company specializes in eCOA for Phase II/III research and has expanded into hybrid and decentralized trial support, with offices in Boston and Tokyo. Kayentis raised additional growth funding in 2023 and partnered with Ametris in 2026 to integrate wearable device adherence monitoring directly into its eCOA platform.

Suvoda

Suvoda provides a unified clinical trial technology platform combining IRT, eConsent, and eCOA, built specifically for complex studies in therapeutic areas such as oncology, central nervous system disorders, and rare disease. Founded in 2013 and headquartered outside Philadelphia, the company states its platform has supported more than 6,000 clinical trials, with 34% of trials that earned FDA approval since 2024 running on Suvoda. The company's product suite now also includes Greenphire's patient payment and travel solutions.

YPrime

YPrime provides a configurable eClinical technology platform spanning eCOA, IRT, and eConsent, and the company states its IRT platform reduces study startup times by roughly 50% while its eCOA launch times run about 47% faster than typical industry timelines. Based in Pennsylvania with more than 15 years of experience, YPrime won both the Innovation Award for AI in Clinical Trials and the Environmental Award for Sustainable Trials at the 2025 Clinical Trials Arena Excellence Awards. The company reports that more than 90% of its trial documentation is now delivered digitally.

Medrio

Medrio provides a clinical data management system combining EDC, eCOA/ePRO, eConsent, and RTSM in a single configurable platform, designed to let non-programmers build and modify study databases without requiring dedicated technical staff. The company states its platform supports study builds in under three weeks, compared to a roughly 12-week industry average, and it serves sponsors, CROs, and sites across the pharmaceutical, medtech, and animal health industries. Medrio has more than two decades of experience in clinical data capture.

THREAD

THREAD provides a decentralized clinical trial and eCOA platform combining eConsent, ePRO, sensors, and telehealth virtual visits, and the company states its Global eCOA Library includes more than 540 pre-validated assessment instruments. Launched in 2016 and backed by healthcare investors Water Street Healthcare Partners and JLL Partners since 2019, the company has expanded its offering through acquisitions including Modus Outcomes, inVibe, and CureClick. THREAD has been recognized as a Leader in Everest Group's Decentralized Clinical Trial Product PEAK Matrix Assessment.

Banook Group

Banook Group operates as a core lab offering cardiac safety, central imaging, endpoint adjudication, and eCOA/ePRO services from a single provider, positioning itself as a European leader in cardiac safety with roots in centralizing ECG data for clinical trials. Founded in Nancy, France in 1999, the company expanded its eCOA capabilities through its 2024 acquisition of B.Research, an Australian eCOA platform, alongside its acquisition of imaging specialist Keosys the same year. Banook now employs close to 120 people across offices in Europe, North America, and Asia-Pacific.

Wemedoo

Wemedoo developed oomnia, a unified clinical trial software platform that combines EDC, CTMS, eTMF, RTSM, eConsent, ePRO, and eCOA as interoperable modules within a single database and login. Headquartered in Switzerland, the company states oomnia has delivered study setups up to 83% faster than traditional fragmented systems and achieved database lock within three days of last patient last visit in a complex adaptive trial. Wemedoo has been recognized by the Society for Clinical Data Management for its unified approach to clinical data management.

Climedo

Climedo provides an integrated eCOA and EDC platform built for real-world and late-phase clinical studies, combining eCRF, ePRO, and eConsent capabilities with real-time dashboards that help sponsors track study progress. Founded in Munich in 2017, the company states it has enrolled more than 1.7 million patients across its studies and serves pharma, medtech, CRO, and academic clients. Climedo positions its platform as particularly suited to non-interventional studies and real-world evidence generation supporting product launches.

Clinion

Clinion offers an AI-enabled eClinical platform combining EDC, RTSM, CTMS, eCOA, and document automation in a single cloud-based system, with AI features spanning study setup, medical coding, remote source data verification, and clinical study report generation. The company, which operates out of Hyderabad, India, states its platform is built for both single-site trials and complex multi-arm global studies while maintaining 21 CFR Part 11 and GDPR compliance. Clinion was recognized by Frost & Sullivan for enabling interoperability and continuity across its integrated eClinical solutions.

Shanhu Health

Shanhu Health provides a suite of clinical trial technology for the Chinese market, including its IRTON randomization and drug supply system, EDC platform, and eCOA solution, alongside broader drug supply chain management services. Founded in 2015 and headquartered in Shanghai, the company states it has served more than 1,500 clinical studies across more than 1,000 Chinese cities and 2,000 institutions, covering more than 2 million study subjects, including international Phase III trials. Shanhu's leadership team includes former staff from Roche, AstraZeneca, and IQVIA.

ClinCapture

ClinCapture provides Virtual Data Capture, a suite of eCOA, ePRO, and eConsent modules built on its Captivate EDC platform specifically to support decentralized and remote clinical trials. The company launched Virtual Data Capture in January 2021 in response to growing pandemic-era demand for remote trial technology, building on capabilities it had already been developing for decentralized studies. ClinCapture's platform is built on an open-source EDC foundation with offline data capture capabilities.

assisTek

assisTek focuses exclusively on eCOA, offering site-based and field-based electronic clinical outcome assessment solutions including Patient Reported Outcomes, Clinician Reported Outcomes, and Observer Reported Outcomes. Based in Doylestown, Pennsylvania and operating for more than 25 years, the company states it has delivered solutions for more than 500 clinical trials while supporting 90 languages across 80 countries. assisTek's TotalSource solutions allow both bring-your-own-device and provisioned-device data collection within the same web-based system.

Explore the full eCOA/ePRO landscape

The companies above represent a portion of a much larger field.

Diligent's platform includes over 215 eCOA/ePRO Vendors, many with Vendor qualification data available on demand. Book a demo to explore Diligent's full vendor discovery database.

This article is intended as an informational overview of vendors operating in this space. Inclusion on this list does not constitute an endorsement, recommendation, or qualification by Diligent.